What are Nitrates (Organic Nitrates)? Nitrates (Organic Nitrates)By Dr. Mahnoor Javed (Pharm D) What are nitrates (organic nitrates): Nitrates (Organic nitrates), (and nitrites) used in the treatment of angina pectoris. They are simple nitric and nitrous acid esters of glycerol. They differ in their volatility. For example, isosorbide dinitrate and isosorbide mononitrate are solids at […]
Half Life and Dose of Medicines
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Eziday Tablets (Losartan Potassium) COMPOSITION Each tablet contains: Losartan Potassium BP/USP 25,50 & 100 mg respectively. DESCRIPTION EZIDAY (Losartan Potassium) is an angiotensin Il receptor (type AT1) antagonist. EZIDAY (Losartan Potassium) is chemically described as 2-butyl-4-chloro-1-[p-(0-1H-tetrazol-5- ylphenyl)benzyl]imidazole-5-methanol monopotassium salt. Its empirical formula is C22H22CIKN60, and its molecular weight is 461.01. PHARMACOLOGY Pharmacodynamics: Angiotensin Il is
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Rolip (Rosuvastatin) Tablets Description Rosuvastatin Calcium, a synthetic lipid-lowering agent, is an inhibitor of HMG-CoA reductase. Composition Rolip 5mg Tablets: Each film coated tablet contains Rosuvastatin (as Rosuvastatin calcium) ……… 5mg. Rolip 10mg Tablets: Each film coated tablet contains Rosuvastatin (as Rosuvastatin calcium)…… 10mg. Rolip 20mg Tablets: Each film coated tablet contains Rosuvastatin (as Rosuvastatin calcium)
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Capoten (CAPTOPRIL) By Dr. Kinza Munir (Pharm-D) Capoten (Captopril) is an oral drug and a member of a class of drugs called angiotensin converting enzyme (ACE) inhibitors. Mechanism of action: Captopril and the other drugs in this class inhibit the converting enzyme peptidyl dipeptidase that hydrolyzes angiotensin I to angiotensin II and inactivates bradykinin, a
Angiotensin Receptor Blocker By Dr. Mahnoor Javed (Pharm-D) ANGIOTENSIN II is a very potent chemical formed in the blood that causes muscles surrounding blood vessels to contract, thereby narrowing the vessels. This narrowing increase the pressure within the vessels and can cause high blood pressure (hypertension). Angiotensin receptor II blockers are medications that block the
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ACE INHIBITORS By Dr. Kinza Munir (Pharm-D) ACE inhibitors, or angiotensin converting enzyme inhibitors, is a class of drugs that interact with blood enzymes to help relax your veins and arteries to lower your blood pressure. ACE inhibitors prevent an enzyme in your body from producing angiotensin II, a substance that narrows your blood vessels. This narrowing
Calcium Channel Blockers By Dr. Syeda Tahira Kazmi (pharm-D) Cardiac effects Calcium-Channel Blockers decrease contractility (negative inotropy) Calcium-Channel Blockers decrease heart rate (negative chronotropy) Calcium-Channel Blockers decrease conduction velocity (negative dromotropy) Vascular effects Smooth muscle relaxation (vasodilation) Calcium channel blockers are prescription medications that relax blood vessels and increase the supply of blood and oxygen
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Beta blockers By DR. Maria Hassan (Pharm-D) Beta blockers, also called as beta–adrenergic blocking agents a class of drugs that bind to beta-adrenoceptors and prevent the binding of norepinephrine and epinephrine to those receptors.So this inhibits normal sympathetic effects, Therefore, beta-blockers/beta–adrenergic blocking agents are also called sympatholytics drugs.that causing decreased heart rate,cardiac contractility,cardiac work load,(AVN)atrioventricular node
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